Wednesday, September 28, 2022

What’s The Difference Between Osteoarthritis And Psoriatic Arthritis

How Does Bursitis Form

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Bursitis can occur from an injury to the joint or from repetitive stress or overuse. Repetitive stress can occur from doing the same activity over and over, like stair climbing, standing for long periods, kneeling for cleaning or gardening, or resting on your elbows for long periods.

Some conditions increase your risk for developing bursitis, including rheumatoid arthritis, gout, and diabetes. The risk of bursitis also increases with age, and being overweight can add stress to the knees and hips, which can increase the risk of bursitis in those joints.3

Treatment Options For Ankylosing Spondylitis Vs Psoriatic Arthritis

There is no cure for either AS or PsA. However, in the case of either condition, medication is critical to treat symptoms, protect joints, slow disease progression, and improve quality of life. Your rheumatologist will best determine the best treatment plan for your specific symptoms and health needs, says Dr. Norton.

Some of the treatments for AS and PsA overlap, though certain medications are better for certain symptoms.

For AS patients: Non-steroidal anti-inflammatory drugs like ibuprofen and naproxen are considered a first-line treatment for ankylosing spondylitis. If these medications dont adequately relieve symptoms, doctors frequently turn to biologics, which are targeted therapies that act on the immune system to stop inflammation. They are either infused with an IV or injected with a syringe or auto-injector pen.

Different biologics act on different parts of the immune system. In AS, commonly used biologics include those that block the protein tumor necrosis factor as well as those that block a protein called interleukin-17 .

FDA-approved anti-TNF biologics for AS include adalimumab , certolizumab pegol , etanercept , golimumab , and infliximab . FDA-approved IL-17 inhibitors for AS include secukinumab and ixekizumab .

PsA patients may also benefit from phototherapy or topical creams to treat skin plaques.

Different Underlying Causes And Types Of Pain

While PsA presents with joint stiffness and swelling due to an overactive immune response, osteoarthritis usually has minimal swelling, and is the result of wear-and-tear to joints. This is why OA affects primarily major or weight-bearing joints, such as the hips, knees, spine, or neck, and typically shows up later in life. PsA can arise across a variety of ages, and often affects the smaller joints of the fingers and toes first . The wear-and-tear of OA is a result of cartilage breaking down. Cartilage normally keeps joints smooth and allows them to function without friction, and without it, can lead to clicking or brittle joints.

Additionally, pain and stiffness in PsA is also typically cyclic, with periods of flare-ups and remission, whereas, OA is a degenerative condition that is constantly getting worse, despite attempts at movement. Finally, the risk factors that lead to the development of each condition are also varied. Obesity, advanced age, previous joint injuries or deformities, repetitive motions, and genetics can all play a role in developing OA, whereas PsAs causes are typically genetics, previous trauma , medications, and stress.

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Do Psoriatic Arthritis And Osteoarthritis Look Similar On X

In osteoarthritis, X-rays may show signs like worn cartilage. In psoriatic arthritis, X-rays can show joint damage in later stages of the disease.

But they arent especially helpful in making a diagnosis in the early stages. X-rays can help make an arthritis diagnosis. But they arent always a slam dunk, Dr. Rosian says.

X-rays can also reveal bone spurs, which can develop in people with osteoarthritis and psoriatic arthritis. Those images may reveal differences between the two diseases:

  • Osteoarthritis bone spurs are more common in areas where cartilage and bone meet.
  • Psoriatic arthritis bone spurs are more likely to form in the regions where tendons and ligaments attach to bone.

To diagnose joint disease, your healthcare provider will probably consider several factors in addition to X-rays, including:

  • Blood tests.

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Anti-inflammatory drugs like ibuprofen and Tylenol are available over-the-counter to alleviate joint pain. The same medications can be prescribed by a doctor. If you are experiencing more severe joint pain, you should see a doctor as soon as possible. If your pain is caused by an injury, you should seek medical attention as soon as possible. You should be aware of the symptoms and make sure that they are not caused by a serious condition.

WhatS The Difference Between Osteoarthritis And Psoriatic Arthritis Inflammation can lead to joint pain. Inflammation can lead to joint damage. Your doctor can prescribe medication to stop the inflammation. While over-the-counter medications can help relieve the pain, they have side effects and should be taken only as directed by your doctor. Your doctor will discuss your treatment options and advise you on any side effects that may occur. If your joint pain is chronic or doesnt respond to these medicines, you may need to see a surgeon.

WhatS The Difference Between Osteoarthritis And Psoriatic ArthritisSymptoms of osteoarthritis usually start slowly and gradually worsen over time. You should visit your doctor if your joint pain persists. A doctor will examine you to make sure theres no swelling or redness in the joints. They may order X-rays and perform lab tests to rule out any underlying diseases. If the diagnosis is confirmed, the goal of treatment is to reduce pain and improve joint function.

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How Do The Signs And Symptoms Differ

Typically, both of these painful diseases can have periods of remission, alternating with flare-ups, which may last for days or even months. With psoriatic arthritis, you may first notice symptoms of psoriasis, and then you may later learn that you also have psoriatic arthritis. In some people, joint pain becomes an issue before the red, itchy, and scaly patches of psoriasis become evident.

Many with psoriatic arthritis experience joint pain, stiffness, and swelling and may also experience pain in any body area. The pain associated with psoriatic arthritis can range from mild to severe. Other symptoms include the cracking, pitting, and lifting of nails and the inflammation and swelling of tendons and ligaments. Fatigue is another challenging symptom that may impact daily life.

Osteoarthritis also causes joint pain and stiffness and a reduction in the joints ability to have a complete range of motion. In addition, this disease may slow your activity because of stiff, swollen joints, typically affecting the hips, hands, knees, and spine. For most with the disease, the symptoms can worsen during and following physical activity and often ease with rest.

Statement Of Literature Search

For the development of this narrative review, publications were identified by a series of searches on PubMed between September 2020 and July 2021. Search terms included AND AND AND AND . Publications that detailed the characteristic clinical manifestations, comorbidities, pathogenesis, biomarkers, treatment recommendations, and differential diagnosis for PsA, RA, and OA were included. References that were determined to be irrelevant on the basis of the authors judgment were excluded from consideration. Relevant references that were cited within the publications included in this review and articles previously known by authors were considered on the basis of the criteria. This review is based on studies that were previously completed and does not contain any novel studies with human participants that were conducted by any of the authors.

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Symptoms Of Ra And Psa

Both RA and PsA cause joint swelling, stiffness, and pain. Although both conditions affect joints in the fingers and toes, they do it in slightly different ways. And each one can cause other symptoms, too.

Rheumatoid arthritis:

  • Often starts in the smaller joints, like the ones in your fingers and toes over time, it may affect other joints, too, like your wrists, knees, hips, and ankles.
  • Usually shows up on the same joints on both sides of your body that means it’s symmetric.
  • Often makes joints feel stiffer in the morning
  • Can lead to fatigue, low-grade fever, and weight loss

Psoriatic arthritis:

  • Can affect joints in the back and pelvis in addition to the ones in fingers and toes
  • Often affects only one side of your body that means it’s asymmetric.
  • Sometimes causes foot pain, especially on the sole of your foot or the back of your heel
  • May make your fingers swell up like sausages
  • May make your nails pit and flake
  • Tends to affect entheses, areas where tendons or ligaments attach to bones

With both conditions, you’ll probably have times when your symptoms get worse. These are called flares. In between these flares are times without symptoms called remissions.

Osteoarthritis Vs Psoriatic Arthritis

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Osteoarthritis is a common condition and one that I have myself. When it comes to osteoarthritis vs. psoriatic arthritis, symptoms can be similar and there are also many differences between the two diseases. One of the critical differences between osteoarthritis and psoriatic arthritis is that the latter is a chronic, autoimmune disease that also causes joint pain. On the other hand, osteoarthritis is joint pain caused by the wearing away of joint cartilage over time.

As it is an autoimmune disease, psoriatic arthritis is the bodys mistaken attack on its healthy skin, nails, and joint cells. There is some indication that our genes may be involved in developing psoriatic arthritis, or it may be due to trauma, or a virus found in the environment. Unfortunately, there is no cure for either of these diseases.

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  • People with PsA may not have psoriasis or may not *realize* they have psoriasis.
  • PsA has many different symptoms.
  • Blood tests can be confusing.
  • Osteoarthritis.
  • Axial spondyloarthritis.
  • Reactive arthritis.

What are the 5 types of psoriatic arthritis? Psoriatic arthritis is categorized into five types: distal interphalangeal predominant, asymmetric oligoarticular, symmetric polyarthritis, spondylitis, and arthritis mutilans.

What is the pain of osteoarthritis like?

The main symptoms of osteoarthritis are pain and sometimes stiffness in the affected joints. The pain tends to be worse when you move the joint or at the end of the day. Your joints may feel stiff after rest, but this usually wears off fairly quickly once you get moving. Symptoms may vary for no obvious reason.

What is the life expectancy of a person with osteoarthritis? Osteoarthritis reduces the quality and quantity of life. By using Quality adjusted life Years it can be said that the average, 50-84 year old, non-obese person with knee OA will lose 1.9 years.

Emerging Lessons From Mri Pattern Of Enthesitis In Oa And Psa

MRI of peripheral joints has long demonstrated a capsular pattern of inflammation in PsA as well as evidence for diffuse enthesitis related to pathology in a proportion of patients . Also, it may be impossible to clearly differentiate OA from PsA DIP disease, with both seeming to have prominent abnormalities in the entheses and ligaments . Even using dynamic contrast enhanced MRI, synovitis assessment as determined by gadolinium-diethylenetriamine pentaacetic acid uptake between the two arthropathies was comparable . Studies have noted that enthesitis-related bone oedema seen in PsA is also common in OA . With respect to spinal disease, an association was evident, with bone oedema at the enthesis attachment observed occasionally in healthy subjects, OA and SpA .

MRI of a PIP joint in OA and PsA demonstrating overlapping features as recently reported

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Warning Signs Of Psoriatic Arthritis

Psoriatic arthritis is a type of arthritis that affects 30% of people with psoriasis, according to the National Psoriasis Foundation. With PsA, your immune system attacks your own body, especially the skin and joints. PsA can mimic other forms of arthritis, such as gout, rheumatoid arthritis and osteoarthritis, says Dr. H. Kevin Jones, FAAOS,, a board-certified orthopedic surgeon at Beaufort Memorial Orthopaedic Specialists. Blood tests can point to other similar conditions and check for signs of inflammation. We can also order X-rays to look for bone and joint changes.

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Differentiating Osteoarthritis And Psoriatic Arthritis Diagnosis

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When we compare psoriatic arthritis and osteoarthritis diagnosis, we focus more on the process of elimination. With osteoarthritis, a doctor will conduct a physical exam, paying close attention to the joints and checking for tenderness, redness, swelling, and range of motion. Imaging and lab tests are also possible. X-rays can show cartilage loss and bone spurs. In complex cases, an MRI can also produce images of bone and soft tissue. As for the lab tests, analyzing blood and joint fluid can be helpful in confirming the diagnosis. On the other hand, there is really no test for psoriatic arthritis. Doctors usually have to rule out other diseases and take a close look at the symptoms a person is experiencing. It is only in later stages of PsA that an X-ray can pinpoint anything. It may show pencil in a cup, which is a situation where the end of the bone gets whittled down to a sharp point. This can support a diagnosis of psoriatic arthritis.

It is possible to have gout along with PsA, so if you have a painful foot joint, especially in the big toe, the doctor may order a test for gout. Fluid from the affected joint is drawn and examined. It is important to note that psoriatic arthritis is often misdiagnosed with gout, because PsA patients can have elevated serum uric acid levels caused by taking low-dose aspirin or by increased skin cell turnover.

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What Causes Oa And Who Is At Risk

OA causes the cartilage inside the joints to break down and wear away. Cartilage is the flexible connective tissue that surrounds the ends of your bones.

In healthy joints, cartilage helps grease the movement of the joint and absorbs the shock of impact when you move. When you have OA, the layers of your cartilage begin to break down.

Without cartilage, your bones rub painfully against each other. This can cause permanent damage to both your joints and your bones.

These risk factors can increase your chances of developing OA:

  • Genes. Certain inherited genetic changes may increase your odds of developing OA. If a family member has the disease, its possible youll get it as well.
  • Age. Your likelihood of getting this type of arthritis increases as you age.
  • Gender. Women are
  • joint support, such as braces
  • alternative remedies

If your joint is badly damaged, you may need surgery. OA surgery replaces the damaged joint with an artificial joint made from plastic or metal.

How Are Ra And Psa Diagnosed

Because these two conditions share similar symptoms, it’s important to get an accurate diagnosis from a rheumatologist. A rheumatoid factor blood test is one way your doctor can tell which condition you have. RF is a protein found in people with rheumatoid arthritis. People with PsA usually don’t have it. Blood tests looking for other antibodies such as anti-CCP can also help differentiate the two.

Another way to tell is to look at your skin and nails. If you have scaly patches on your skin, pitting and flaking on your nails, or both, you have PsA.

Once you’ve had the disease for a while, X-rays might also be able to distinguish the two conditions.

It is possible to have RA and PsA together, but it’s rare. If you do have both, many of the treatments, including some medications, will work for both conditions.

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Symptoms Of Psoriatic Arthritis

The severity of the condition can vary considerably from person to person. Some people may have severe problems affecting many joints, whereas others may only notice mild symptoms in 1 or 2 joints.

There may be times when your symptoms improve and periods when they get worse .

Relapses can be very difficult to predict, but can often be managed with medicine when they do occur.

Psoriatic Arthritis And Osteoarthritis: Overlapping Features

So why can psoriatic arthritis be mistaken for osteoarthritis when it sounds so different? This is due to the fact that osteoarthritis and psoriatic arthritis have overlapping features.

Both OA and PsA often begin after the age of 40 and are commonly linked to excess body weight. They are both associated with joint injury. It is important to understand that even though OA is a wear and tear disease, there can be inflammation in the early stages. It is also possible that someone can have OA and PsA at the same time. Another shared characteristic is pain in the spine. While this is more common in OA, it can also happen in PsA sufferers.

Although more research is underway, there is some suggestion that psoriatic arthritis may possibly trigger secondary osteoarthritis. In other words, some inflammation from PsA may be able to cause wear and tear.

Osteoarthritis can start with a small joint swelling that looks like psoriatic arthritis. However, it can later develop into a bony growth known as Heberdens or Bouchards nodes. Often, these growths indicate osteoarthritis in the diagnosis, but they can take several years to form.

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Rheumatoid Arthritis And Psoriatic Arthritis: The Similarities And Differences

All forms of arthritis involve tenderness and swelling of the joints. And, at first glance, psoriatic arthritis can be very hard to differentiate from other common types of arthritis, including rheumatoid arthritis and osteoarthritis.

Because psoriatic arthritis symptoms can overlap with those of rheumatoid arthritis and osteoarthritis not just swollen, achy joints but also stiffness and chronic fatigue diagnosing this autoimmune disease can be tricky.

Unlike rheumatoid arthritis, there is no blood test that can determine if a person has psoriatic arthritis, says M. Elaine Husni, MD, MPH, a rheumatologist at the Cleveland Clinic in Ohio.

Psoriatic arthritis can also affect the body in different ways depending on the person and how advanced the disease is, says Dr. Husni. As a result, a rheumatologist may need to examine a patient several times and run a number of tests before having enough information to make a definitive diagnosis.

One unique symptom of psoriatic arthritis that doctors look for is the presence of psoriasis, a condition that causes thick, discolored, scaly skin patches known as plaques, as well as pitted nails or nails that separate from the nail bed, according to the American Academy of Dermatology.

Like psoriatic arthritis, psoriasis stems from a faulty immune response, in which the immune system mistakenly attacks healthy cells and tissues.

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