How Cortisone Injections Work
Cortisone injections are used to treat many joint problems, including bursitis, tendonitis, trigger finger, carpal tunnel syndrome, tennis elbow, knee arthritis, and many types of overuse injuries.
Cortisone is a type of steroid hormone that work by decreasing inflammation. Inflammation is the body’s normal response to an injury, infection, or disease as a means to heal itself. However, when a condition is persistent and the inflammation is chronic, the symptoms of inflammationincluding pain and swellingcan become intolerable.
How Can Steroid Side Effects Be Minimized
To minimize the side effects of steroids, doctors follow these guidelines:
- Use steroids only when necessary.
- Monitor closely to detect the development of serious side effects.
- If possible, use steroid injections for problems in a specific area.
- Use the minimal dose required to gain control of the disease.
- Reduce the dose gradually if the disease remains under control.
- Monitor blood pressure often and treat if necessary.
- Recommend calcium supplements, vitamin D, and bone-building prescription medications to help maintain bone strength .
- Have your bone density checked every one to two years.
What Is Cortisone Used For
Cortisone shots can be used to treat inflammation of small areas of the body, like inflammation of a specific joint or tendon. They can also treat inflammation that’s widespread throughout the body, like when you have allergic reactions, asthma, and rheumatoid arthritis, which affects many joints.
Your doctor may prescribe a cortisone shot for:
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Altered Response To Physical Stress
If you take corticosteroids for more than two weeks — even if you then wean yourself off the medication — your adrenal glands may become sluggish, and your body may not be able to respond normally to physical stress. This is called adrenal insufficiency, and it may last up to a year after you stop the medication. Its potentially life-threatening because youre not able to respond normally to a serious illness, surgery or an injury. Solution: If youre taking corticosteroids or have taken them in the past year, be sure to tell your dentist, doctor and any providers treating you in any emergency or during surgery. In such cases, your doctors likely to give you supplemental or stress steroids to make up for any adrenal insufficiency.
Q: Does Cortisone Cause Any Damage To The Joint Tissues

A: Usually there isnt any joint damage from the cortisone, but some studies have shown that it can cause damage in tendons and may predispose people to tendon rupture. Another study shows cortisone injections in knee joints can damage remaining cartilage within the knee.
This is why its important to diagnose and treat the underlying conditions which can lead to arthritis, such as obesity, malalignment, poor body mechanics and inflammatory/autoimmune disorders.
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Repeat Cortisone Injections Not Uncommon In Patients With Chronic Inflammatory Condition
Dear Mayo Clinic:
How do cortisone shots work to relieve pain? It appears that they only provide temporary relief and are often given multiple times. Is there a point at which frequent cortisone shots can be harmful to the body? How much is too much?
Answer:
Injections of cortisone, or a similar corticosteroid, decrease inflammation in an injured part of the body. When body tissue is injured, a series of events occurs locally and within the bloodstream to promote healing. Inflammation can result from this healing process and, frequently, the inflammation causes pain. Injecting corticosteroids into the inflamed area helps to calm the inflammation. As the inflammation subsides, the pain does too.
Cortisone is naturally produced in the body’s adrenal glands. It was discovered in the 1940s by Mayo Clinic researchers, Edward Kendall, Ph.D., and Philip Hench, M.D., who first used it to treat joint disorders. Its powerful anti-inflammatory effect produced such dramatic results in people with rheumatoid arthritis that it was hailed as a miracle drug. In 1950, Drs. Kendall and Hench were awarded the Nobel Prize in Medicine for the discovery of cortisone.
Side effects may include weakening of the joint, increased blood pressure, elevation of blood sugar, and decreased ability to fight infection. Evidence of these side effects should be reported to the doctor monitoring the condition.
â Paul Carns, M.D., Anesthesiology, Mayo Clinic, Rochester, Minn.
Side Effects Of Cortisone Injections
Cortisone injections, like many treatments, have their side effects despite great benefits. These health risks include:
- Weakening and suppression of the immune system
- Weakening or rupture of tendons
- Thinning and weakening of skin, soft tissue and bone
- Bone death due to lack of blood circulation
- Temporary joint pain and inflammation
- Cartilage deterioration
- Joint infection
Patients put themselves at greater risk for contracting these side effects if they receive cortisone treatments more often than their physician recommends. Additionally, many doctors are hesitant to give cortisone shots to diabetic patients, due to the drugs ability to raise blood sugar levels.
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How Long Does A Cortisone Shot Work For Specific Conditions
Cortisone shots are used broadly and effectively for a range of orthopedic conditions. There are no medical restrictions about the types of conditions that can be treated with these injections. However, because cortisone acts to suppress inflammation, conditions that cause acute inflammation are most likely to respond favorably.
When Can A Person Expect Pain Relief From A Steroid Injection
Cortisone injections often lead to a temporary increase in inflammation and pain. This can last up to 48 hours after the shot. After 48 hours, the pain and inflammation caused by your RA should decrease.
According to the Cleveland Clinic, it may take up to seven days before the body responds to a corticosteroid injection. The positive effects from an injection typically last for two months, although they can also last longer.
Despite this delay, corticosteroids are still the quickest way to limit inflammation in the body. It is important to note, however, that injections are not a permanent fix for RA.
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When Should Steroid Injections Not Be Used
Steroids should not be injected when there is infection in the area to be targeted or even elsewhere in the body, because they could inhibit the natural infection-fighting immune response. Also, if a joint is already severely destroyed, injections are not likely to provide any benefit.
If someone has a potential bleeding problem or is taking anticoagulants , steroid injections may cause bleeding at the site. For these people, injections are given with caution.
Frequent steroid injections, more often than every three or four months, are not recommended because of an increased risk of weakening tissues in the treated area.
Talk With Others Who Understand
On myRAteam, the social network for people with rheumatoid arthritis and their loved ones, more than 185,000 members come together to ask questions, give advice, and share their stories with others who understand life with rheumatoid arthritis.
Have you received cortisone injections for your rheumatoid arthritis? If so, what was your experience? Share your story in the comments below, or start a conversation by posting on your Activities page.
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Cortisone Shot Disadvantages And Side Effects
Short-term side effects are rare, but they can include the following:
-
Shrinkage and lightening of the color of the skin where you get the shot
-
Bleeding from broken blood vessels in the skin or muscle
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Soreness where you get the shot
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Aggravation of inflammation in the area injected because of reactions to the medication
Tendons can be weakened by corticosteroid injections, and tendon ruptures have been reported.
If you have diabetes, cortisone injections can raise your blood sugar. If you have an infection, these shots can make it harder to recover. You may not be able to get this treatment if you have problems with blood clotting.
Long-term side effects depend on the dose and how often you get this treatment. With higher doses and frequent shots, potential side effects include:
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Thinning of the skin
-
Cataract formation
-
Thinning of the bones
Rare but serious damage also can happen to the bones of the large joints .
When You Might Need A Steroid Injection For Your Foot Or Ankle

There are many reasons why your doctor may suggest a steroid injection for your foot or ankle pain. It can help if medication or physical therapy hasn’t helped with the pain. However, rehabilitation includes shots along with other medications or physical therapy.
A steroid shot is an option before surgery on your foot or ankle. You may prefer a steroid injection. Oral steroids that you take by mouth have more side effects. There are some risks with a steroid injection. A steroid injection in your foot or ankle may cause the following concerns:
Because of these issues, your doctor may recommend only a few treatments a year.
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What Are The Possible Side Effects Of Oral Steroids
Side effects are more common with a higher dose and longer treatment. Side effects are much more common with oral drugs. Some side effects are more serious than others. Common side effects of oral steroids include:
- Water retention, swelling
- Worsening of diabetes
Please note: The side effects listed are the most common side effects. All possible side effects are not included. Always contact your doctor if you have questions about your personal situation.
What Can You Expect When You Get A Steroid Injection
Before your injection, you may need to stop taking certain medications. Talk to your doctor about what medications you take. Dont make changes unless they tell you to.
Steroid injections must be done in a doctors office or hospital. Once you get to your appointment, your doctor will go over the procedure and have you sign a consent form. Then theyll have you lie in a way that allows them to access the injection site.
Your doctor may then use an ultrasound to figure out where exactly to give you the injection. Once they have the right place, theyll inject a mix of the steroid and a numbing medication. The shot may be uncomfortable, but the numbing medication will take effect quickly.
Injections can be given into:
- bursae, which are fluid-filled sacs between some tendons and joints
Youll need to keep the injection site clean and dry for the next 24 hours.
The site may be sore for a few days. You can use a cold pack on the injection site if you need to, for up to 10 minutes at a time. Wait at least 24 hours before using heat on the injection site.
Steroids can also be given through the veins . This method is usually used for autoimmune flares.
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Cortisone Injections For Rheumatoid Arthritis: What To Expect
Cortisone injections, also called corticosteroid or steroid injections, are shots that can alleviate pain and decrease inflammation in people with rheumatoid arthritis . Corticosteroids are anti-inflammatory medications that can be given as injections, creams, oral medications, and more.
Steroid injections may be used to treat other types of pain, including back pain or tendinitis. Cortisone injections to relieve joint pain are different from anabolic steroids, which athletes may take to boost their performance.
Understanding The Impact Of A Leading Arthritis Treatment
If you experience knee pain because of arthritis, your doctor can prescribe you a number of options: physical therapy, medication, injections, and even surgery. It all depends on the details of your specific diagnosis.
Because there is no known cure for any form of arthritis , doctors find many patients are able to manage their symptoms even if only temporarily with cortisone shots. As the most common path of treatment to relieve arthritis pain, these injections contain corticosteroids, a drug that mimics hormones that naturally occur in the body to reduce inflammation. By injecting a corticosteroid into arthritic knee joints, doctors can lower knee pain and increase mobility in patients for weeks, sometimes months.
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Should You Use Ultrasound For A Cortisone Shot In Shoulder
Why should we use ultrasound for injections? Firstly, using ultrasound increases the accuracy of a steroid injection. Greater accuracy can reduce side effects such as skin thinning and tendon weakening. Secondly, we know that ultrasound improves the impact of an injection. Finally, we do ultrasound injections in an office, which means that these injections are cheaper than those done in a hospital.
What Happens Before Treatment
The doctor who will perform the procedure reviews your medical history and previous imaging studies to plan the best location for the injections. Be prepared to ask any questions you may have at this appointment.
Patients who take aspirin or a blood thinning medication may need to stop taking it several days before the procedure. Discuss any medications with your doctors, including the one who prescribed the medication and the doctor who will perform the injection.
The procedure is usually performed in an outpatient special procedure suite that has access to fluoroscopy. Make arrangements to have someone drive you to and from the office or outpatient center the day of the injection.
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Preparing For A Steroid Joint Injection
Your doctor or healthcare professional will explain how to prepare for your procedure. They may give you an information leaflet with details about steroid joint injection treatment.
Let your doctor know about any medicines youre taking. If you take a medicine that thins your blood , your risk of bleeding into the joint is higher. So, you may need to have a blood test before a steroid joint injection to check how well your blood clots. For a similar reason, its important to let your doctor know if you have a health condition that affects the way your blood clots for example, haemophilia.
Its also important to let your doctor know if you have diabetes. This is because a steroid joint injection may raise your blood sugar for several days. See Diabetes and steroid joint injections in our section about recovery.
You dont usually need to make any other special preparations before you have a steroid joint injection. Its best to wear comfortable clothes that allow easy access to the joint that youre having injected.
Check with your doctor or healthcare professional if youll be able to drive after your joint injection. Its a good idea to ask friends or family for a lift home. If you have a local anaesthetic, your joint area might feel numb so it might be difficult to drive.
Also, be prepared to rest the affected joint for a day or two afterwards. Make sure you get everything you need and stock your fridge in advance.
Steroid Injections For Arthritis

Arthritis, even when contained to a small joint, can wreak havoc. If you have the issue already, you are well aware of that fact. You might try to grasp a pen, open a jar, or use the hand and find yourself unable to do so. The use of an injection directly into the joint affected by arthritis will usually help to address inflammation.
What this means is quite simple: Get that targeted injection, and there is an immediate reduction in pain, redness, and swelling. In addition to addressing these issues, they are usually, according to WebMD, generally well tolerated and are less likely than other forms of steroid medications to produce serious side effects.
If you are someone with arthritis in your hand or fingers, and your doctor is recommending treatment, it can be useful to understand how and why it will help.
There are more than 110 kinds of arthritis, though it is most likely RA that has affected your hands. It is an autoimmune condition that causes the body to attack healthy joints, and will eventually cause more than just chronic pain or swelling. It breaks down cartilage and leads to stiffness, deformity, and loss of function in the joint.
When getting treatment, a physician will simply cleanse the area for injection and then evaluate whether excess fluid will need to be removed. If so, they insert a syringe and remove the fluid to relieve pain and pressure. The removal of the fluid also helps the steroid injection work more efficiently.
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What About Prp Injection For Thumb Arthritis
Although a PRP injection has shown a good effect on knee arthritis, there is no evidence that PRP helps thumb arthritis. Nevertheless, we would think about a PRP injection for thumb arthritis in people who have failed other treatments including a cortisone injection.
If a CMC joint injection is not effective, we would then consider a surgical procedure of fusion or bone excision.
Any Precautions After Getting Steroid Shots For Arthritis
Your doctor will likely recommend that you go easy on the affected joint for a few days after the steroid injection. If you got a shot in your knee, this means resting/elevating it when you can throughout the day. If you got a shot in your shoulder, you should avoid lifting heavy things. You should use ice on the area to help swelling go down, but not heat therapy. Here are more examples of how to use cold therapy for arthritis pain.
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What Is Treated With Steroid Injections In The Finger
Though you may already know why a physician has recommended that you go for steroidal injections in one or more fingers, it helps to understand that they are a common non-operative treatment for multiple musculoskeletal conditions, of the hand. Experts frequently recommend them to patients with:
- Carpal tunnel syndrome
- DeQuervains tendonitis
- Joint synovitis or arthritis
- Shoulder bursitis
What Is A Steroid Joint Injection
A steroid injection includes both a corticosteroid and an anesthetic numbing agent . The drugs are delivered to the painful joint, inside the joint capsule.
Corticosteroid injections can reduce inflammation and can be effective when delivered directly into the painful area. The pain relief can last from days to years, allowing your condition to improve with physical therapy and an exercise program.
Injections can be made in the following areas:
- knee, ankle and foot
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