Saturday, January 28, 2023

Does Turmeric Relieve Arthritis Pain

Turmeric Kicks The Pets Hip Pain Away

Turmeric: for Arthritis (Joint Pain)

A dog owner shares a story about their pet dog, Samson who had injured his right hip and had difficulty in walking or getting up. The dog struggled with his pain o the extent that he would old his right leg up.

The dog was diagnosed with inflammation and was recommended turmeric. The owner gave the dog ¼ tsp of turmeric with dog food and water every morning and within a few days, the dog stopped holding his leg up. In a few weeks time, he had started running.

Still, the dog relapsed and started limping again and was kept on painkillers.

Gradually the owner took the dog off meds and started him with turmeric again. The dog recovered again and his gait became normal. The owner concluded that it was turmeric that helped control his pets inflammation.

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Data Sources And Selection Criteria

The following electronic databases were searched: PubMed, Embase, Cochrane Library, Korean databases such as DBpia, the Research Information Service System , the Korean Information Service System , Chinese medical databases such as China National Knowledge Infrastructure and the Chinese Scientific Journals Database, the Indian Medical Journals and the Indian Journals. Dissertations were also included. The search was conducted in the databases using proper languages of English, Korean, and Chinese. The following keywords of Medical Sub Headings were used as search terms: curcumin,curcuma,turmeric,Curcuma domestica,Curcuma Longa,arthritis,osteoarthritis,randomized,controlled trial, and clinical trial. In the systematic review, all RCTs were included from the available databases up to April, 2016, that had examined the effects of turmeric and curcumin on arthritis.

Benefits Of Turmeric In Osteoarthritis

Osteoarthritis occurs when there is wear and tear to the cartilage. This is the most commonly occurring of all types of arthritis. When cartilages break down, bones begin to rub against each other causing swelling, pain and stiffness.

The range of motion of joints gets affected and there can be muscle weakness and growth of Herberdens nodes at the joints. Osteoarthritis occurs in the joints of the hips, knees, hands, and spine.

Age, metabolism, genes, mechanical and chemical factors could be some causes of contracting osteoarthritis. Those who are obese, construction workers or athletes who overwork their joints could also at risk. Treatment options include exercise, lifestyle changes, and medications.

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The Yellow Spice Contains A Compound That Helps Reduce Inflammation And Pain

Image: Kari Perrin

Turmeric, a yellow root deriving from the ginger family, is not just a flavorful addition to many tasty dishes. The spice possesses an active ingredient that is shown to have a positive effect on inflammation and joint pain. For those with arthritis and other inflammatory joint diseases, turmeric could be a powerful addition to their treatment. Whether you decide to add it to a smoothie, use it to make a curry or take in a capsule, the root may be a helpful natural remedy.

According to Dr. Myrdalis Díaz-Ramírez of Sarasota Pain Relief Centers, many people take 1,000-milligram capsules of the root’s powder.

“There is a National Institutes of Health section that studies alternative medicine and they have found signs for further study of the plant,” says Díaz-Ramírez. “Research has shown preliminary improvement in some patients.”

What makes turmeric so effective? Díaz-Ramírez says the active ingredient within the root is curcumin, a powerful compound and antioxidant that contains anti-inflammatory properties. The curcumin content of turmeric is only about 3 percent by weight, so supplements containing higher curcumin content can be even more beneficial.

“The National Institutes of Health doesn’t have the exact science or measures needed for it to be effective. It is different for every patient,” say Díaz-Ramírez. “But while there is no official recommendation from the U.S. government, there are supplements people can try.”

Changing Your Diet May Also Help Relieve Knee Pain

Does Turmeric Help With Joint Pain?

Theres strong evidence that eating the Mediterranean diet may provide significant knee pain relief in people with OA.

Researchers reviewing three different studies found that people with symptoms of arthritis had an improved quality of life after starting the Mediterranean diet.

According to the study, the Mediterranean diet may benefit OA because of its anti-inflammatory properties, tendency to reverse metabolic syndrome , and reduce obesity.

Researchers say the diet is also rich in polyphenols , which can prevent inflammation and cartilage destruction, and this could also be why it shows benefit.

While there is no specific diet that works as a cure for arthritis, various studies have shown that a Mediterranean diet can help fight the inflammation associated with arthritis and slow the disease progression, said Gupta.

As always, getting the right dosage is key to staying healthy. While turmeric may help joint pain, more is not always better.

Consuming large amounts of turmeric can have side effects.

Subjects in a 2006 small dose-response study reported a range of adverse reactions from using 500 mg to 12,000 mg of curcumin daily, although the researchers found overall participants tolerated the high levels of the spice.

Of 24 participants, seven reported side effects that included headache, diarrhea, and skin rash. All but one of the people with side effects were taking over 4,000 mg of turmeric.

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Turmeric And Arthritis In Animal Studies

Animal studies utilizing turmeric extract have demonstrated an anti-inflammatory effects on joints. A 2010 study built on previous research and investigated whether turmeric essential oils protected the joints in the rats. The results were positive, indicating a potential for a positive effect in humans, as well, but more research is needed.

Can Turmeric Relieve Arthritis Joint Pain & Inflammation

You can’t run from father time. Its effects manifest in even the most health-conscious individuals. Arthritis is one of its symptoms. Even in younger folks, joint pain may occur as a result of overtraining. In any case, how do you alleviate an aching knee or elbow? At UMZU, we are advocates of the holistic path. This includes the use of natural remedies like turmeric and other herbal medicines. Its use for joint pain is well established in various scientific literatures.


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Lets Talk About Adverse Effects

Turmeric is lauded as safe, and studies do seem to indicate that it is safer than NSAIDs. However, turmeric does have a blood thinning effect and could have an interaction with other blood thinning medication, such as aspirin and warfarin. Avoid turmeric if youre having surgery or are pregnant and if you have gallbladder disease.

It Is Clinically Proven To Benefit In Osteoarthritis

Turmeric – Does It Work For Arthritis And Joint Pain?

A review study in the Journal of Medicinal Food, 2016 that most clinical trials report the reduction in disease activity and osteoarthritis symptoms when on turmeric and curcumin treatment.

Curcumin is also found to be as effective as painkillers.

Overall a dose of 1000mg of turmeric extract per day is beneficial in arthritis treatment.

A study was conducted in Kyoto Medical Centre where 40 individuals with osteoarthritis were treated with Theracurmin or placebo for 8 weeks. The paper stated that Theracurmin is 27 times more bioavailable than curcumin powder.

Individuals received either placebo or 180mg curcumin per day for 8 weeks. At 8 weeks, theracurmin significantly attenuated pain and disease activity in patients.

Also, it reduced dependence on an anti-arthritic drug, celecoxib.

Belcaro et. al studied the effect of Meriva, a specialized formulation of curcumin in 100 osteoarthritis patients for 8 months. A significant reduction in inflammatory enzymes and improvement in clinical symptoms was observed.

Researchers suggested that Meriva can be considered as a long term therapy in osteoarthritis.

Combination of curcumin with exercise therapy and chondroitin sulphate and glucosamine sulphate is also found to help in osteoarthritis.

What does this mean?Various studies in humans have proved that curcumin and turmeric extract can attenuate symptoms in osteoarthritis and prevent disease progression.

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More Effective Than Placebo

In another study, published this week in the Annals of Internal Medicine, researchers at the University of Australia in Tasmania assigned 70 participants, over age 40, with knee osteoarthritis and swelling diagnosed by ultrasound, to receive either 1000 mg per day of turmeric or a placebo.

After 12 weeks, the randomly controlled placebo trial found that an extract of turmeric was more effective than a placebo in reducing knee pain in people with knee osteoarthritis.

Those taking turmeric reported significantly less knee pain at the end of the study, according to the standardized questionnaire.

Researchers emphasized that more research is needed, and the only limiting factor of their study was the small number of participants.

This research also received funding from Natural Remedies PVT Ltd, a company that offers Ayurvedic medicines and herbs.

While this may indicate a conflict of interest, previous research also supports this spices effectiveness for pain relief.

It Works As An Antioxidant In Osteoarthritis

Curcumin and other curcuminoids are natural antioxidants. Grover et. al have identified the utility of curcumin as an antioxidant supplement in osteoarthritis.

Oxidative stress is the imbalance between prooxidant and antioxidant agents in the body and this contributes to the progression of the disease.

A study published in the Journal of Dietary Supplements, 2016 demonstrated how curcuminoids supplementation reduces oxidative stress in osteoarthritis.

40 patients suffering from knee osteoarthritis were enrolled in the study. They were given 1500mg curcuminoids with 15mg piperine every day in 3 divided doses or matched placebo for 6 weeks.

At the end of the study, it was observed that curcuminoid supplementation improved antioxidant defenses by raising the level of antioxidant enzyme and reducing the levels of prooxidant enzymes.

Researchers concluded that this could be one of the ways by which curcuminoids relieve osteoarthritis symptoms.

What does this mean?Curcumin and other curcuminoids present in turmeric are natural antioxidants and can help improve antioxidant defences in osteoarthritis patients. This can indirectly relieve osteoarthritis symptoms.

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Be Aware Of Drug Interactions

Turmeric is generally considered safe when taken as recommended. However, patients should also be aware that in high doses, turmeric can act as a blood thinner, so it should be avoided if you are taking blood thinners, are having surgery, or are pregnant. There has been some reported research on turmeric reducing the tolerance to and effectiveness of opioids, so be sure to speak to your doctor if you are on opioid therapy and considering trying turmeric. Prolonged use of curcumin may also result in gastrointestinal problems. As always, consult your physician before adding any supplement to your dietary regimen.

Evidence That Turmeric Compounds Could Help Relieve Arthritis

How Does Turmeric Help With Joint Pain?

Although multiple animal studies indicate that turmeric and its curcumin compounds are likely to help prevent osteoarthritis, rheumatoid arthritis, and possibly even arthritis related to psoriasis, researchers suggest it may not be beneficial in treating the condition. However, clinical studies in human patients with both osteoarthritis and rheumatoid arthritis are more promising. Results indicate that turmeric’s curcumin compounds in forms that increase its bioavailability do reduce the symptoms of arthritis.

These include:

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What Does The Research Say

Turmeric contains several different compounds, including curcumin. Much of the available scientific research focuses specifically on curcumin rather than turmeric as a whole.

However, some studies do suggest that both turmeric and its compounds may be helpful for the symptoms of arthritis, including RA.

A 2016 systematic review examined data from eight randomized clinical trials that investigated the effectiveness of turmeric and curcumin extracts for treating symptoms of joint arthritis.

The authors concluded that there was enough evidence to suggest that taking 1,000 milligrams of curcumin each day for 812 weeks can help reduce pain and inflammation due to arthritis, particularly osteoarthritis. The results also indicated that curcumin extracts might be as effective as taking nonsteroidal anti-inflammatory drugs , such as ibuprofen and diclofenac .

However, the authors stated that the small size and moderate quality of the studies mean that further research is necessary to confirm these findings. In the meantime, they recommend that people with arthritis use curcumin as a dietary supplement in addition to conventional therapy.

A 2017 study involving 36 people with RA tested a bioavailable formulation of curcumin. After 90 days of treatment, the participants who took curcumin reported significant improvements in their pain and inflammation compared with those in the placebo group.

How To Get Turmeric In Your Diet

Turmeric is usually found in root form or in a powder and can be sprinkled on veggies and rice or added to soups and smoothies. You can even drink turmeric tea.

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However, curcuminthe active compound that accounts for much of turmerics health benefitsonly makes up 3 to 5% of turmeric.

In order to get enough curcumin for its benefits to be effective, many experts recommend that people take curcumin supplements. Advocates suggest a daily curcumin supplement of 200 to 1000mg that contains 95% curcuminoids.

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Green Salad With Turmeric Dressing

Leafy green vegetables are nutritious and are among the best vegetables for people with arthritis to eat, according to the Arthritis Foundation. A base of spinach, kale, or swiss chard combined with other veggies, such as carrots and peppers, will create a filling salad that can help fight inflammation.

This recipe for an anti-inflammatory turmeric dressing can further enhance the inflammation-fighting power of vegetables. It includes a coconut cream and olive oil base combined with other seasonings and flavors.

Turmeric Recipes That Can Help Relieve Arthritis Symptoms

Does Curcumin (Turmeric) Reduce Knee Pain?

10 Turmeric recipes that can help relieve arthritis symptoms for News Target

Turmeric is a rich and aromatic spice popular in Indian and Middle Eastern cuisines. But on top of its uses in the kitchen, turmeric also has medicinal properties that render it a potent natural medicine for numerous ailments, from sprains to arthritis.

In fact, recent studies on turmeric indicate that turmeric is a promising medication for pain relief among arthritic patients, according to a pair of researchers from Duta Wacana Christian Universityin Indonesia.

The pair examined the results of randomized controlled trials on turmeric and arthritis pain. Their findings are published online in the Asian Journal of Pharmacy and Pharmacology.

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Just Like Nsaids Turmeric Inhibits Cox Enzymes

Curcumin is proven to effectively regulate activities of cyclooxygenase and lipooxygenase enzymes.

Regulation of both these enzymes helps in curbing inflammation and preventing spread of many diseases.

Curcumin is better than many painkillers as it can selectively inhibit COX-2 or it can inhibit COX/LOX at the same time. A research study proves that curcuminoids ability in reducing COX-2 enzyme is equivalent to that of painkiller, diclofenac sodium.

Summary Of Included Studies

A total of 10,293 studies were found in the initial electronic searches from PubMed, Embase, WANFANG, CNKI, RISS, KISS, and IndMED, and 28 duplicates were removed. From the remaining 10,265 studies, those potentially not related RCT studies about curcumin and arthritis were removed and the details of the removed studies were as follows: 176 in vitro studies, 7367 animal experiments, 1198 no relation to arthritis, 1325 no relation to turmeric or curcumin, and 150 nonarthritis orthopedic-related studies . Further evaluation of the full texts resulted in the elimination of 8 studies with lack of data and 33 studies due to non-RCT. Finally, eight RCTs met the inclusion criteria . The eight RCTs were used for the systematic review., The subject characteristics and intervention strategies of the included RCTs are summarized in and intervention results and adverse events are organized in .

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It Increases The Efficacy Of Other Anti

Curcumins anti-inflammatory and pain relieving action help potentiate the action of various medications prescribed in arthritis.

A study was conducted where curcumin was evaluated as adjuvant therapy in osteoarthritis. Patients were given either 75mg of diclofenac sodium per day alone or 75mg of diclofenac sodium plus 1000mg of curcuminoids per day.

The study lasted for 3 months. Though no statistically significant differences were observed, patients receiving the combination therapy reported a better reduction in paib and improvement in the quality of life.

Celecoxib is a commonly prescribed anti-arthritic drug that acts on inflammatory enzyme COX to reduce inflammation and prevent the progression of the disease. A study published in Rheumatology 2006, reveals that curcumin enhances the activity of celecoxib to prevent disease progression in osteoarthritis.

It does this by increasing the activity of celecoxib in inhibiting the growth and terminating damaged cells in osteoarthritis that spread inflammation in osteoarthritis.

Researchers suggest that this activity of curcumin may enable the use of a safer and lower dose of celecoxib with better outcomes in osteoarthritis.

What does this mean?Curcumins ability to enhance the activity of anti-arthritic drugs makes it a suitable adjuvant therapy in osteoarthritis. It also reduces side effects of conventional treatment.

Bottom Line On Turmeric Or Curcumin For Osteoarthritis

Do Turmeric Pills Help Arthritis?

Neither turmeric or its active ingredient curcumin has been tested with the numbers and controls that are needed to approve medications by the FDA. That said, the little research we do have available in controlled human studies suggests that these nutraceuticals may have an anti-inflammatory effect that could benefit osteoarthritis. If you are interested in trying one of these supplements, start by discussing the risks and benefits with your health care provider.

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Use In Relieving Inflammatorypain & Other Conditions

While many patients are prescribed anti-inflammatory medications to relieve symptoms of chronic pain, long-term use sometimes cannot be sustained due to side effects on the immune system as well as cardiovascular and gastrointestinal complications. Herbal therapies like turmeric offer a great way to supplement those medications with fewer side effects.

Studies have shown that patients diagnosed with conditions caused by inflammation, such as osteoarthritis, have seen improvement in pain, overall function, and quality of life when using the product.

Other uses for turmeric include treating liver and digestive problems. The substance has also shown to be effective in reducing skin irritation resulting from radiation treatments for breast cancer. Ongoing preliminary studies are looking at using curcumin as a possible treatment for other cancers and diabetes, as well as an aid in reducing cholesterol.

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