Friday, April 19, 2024

Can Fish Oil Help Arthritis

It Reduces The Side Effects Of Conventional Painkillers

Benefits of fish oil for arthritis

EPA present in fish oil has an anti-ulcerogenic effect. Study shows that fish oil consumption can protect from gastric lesions or erosions in the gastric mucosal lining caused by NSAIDs such as aspirin and indomethacin.

Animalstudies show that fish oil can protect from indomethacin-induced gastric lesions.

Park et. al that omega 3 fatty acid based NSAID can prove to be the next generation GI safe NSAID.

Omega 3 fatty acid can help in protecting from gastric side effects and cardiovascular effect associated with NSAID.

A study by Faust et. al in humans suggests that dietary fish oil is inefficient in protecting the stomach from aspirin-induced gastric damage.

Kremer et. al demonstrated that 8g supplementation of fish oil in individuals taking pain killers did not show significant changes but a definite reduction in stomach inflammation was observed.

What does this mean? Fish oils anti-inflammatory effect can protect from gastric damage and cardiovascular risk associated with NSAIDs.

What Are Other Things To Consider

When taken at the right dose, Omega 3s have relatively few side effects. If a dog takes Omega 3s with aspirin, they might experience blood thinning. NOTE: Aspirin is NOT recommended for dogs.

The most common side effect is diarrhea, particularly at higher doses. CARE recommends gradually increasing your dogs daily dose of Omega 3s until they reach the recommended dose for their weight.

Fish oils are highly prone to oxidation, so its important you store them away from light. The formula should also contain adequate levels of Vitamin E or other antioxidants as preservatives if preservatives are not added , the product must be kept refrigerated.

Flaxseed are not readily converted to the active forms EPA & DHA in pets and CARE does not recommend using flaxseed as a source of Omega 3s.

Key Take-Aways

  • The most common side effect with Omega 3s is diarrhea. Increase the amount your dog receives gradually until they reach their recommended daily dose.
  • Flaxseed is not a good source of Omega 3s for dogs, as animals dont readily convert it to the active forms of EPA and DHA
  • You can choose to feed your dog fish such as sardines or anchovies, use a food supplemented with fish oil, or give them supplements.

Links and Resources

Fish Oil And Inflammatory Bowel Disease

A small monitored study showed a reduction in Inflammatory Bowel Disease after been administered Fish Oil for a certain period of time thus establishing the fact that fish oil can positively improve the condition of the patient with an inflamed bowel.

Another controlled study at the Boston University Medical Center suggested that patients with gastric inflammations can benefit from taking dietary fish oil supplements.

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Fact : Fish Oil Can Be Consumed In Pill Form Or Through Cold Water Fish

Feeling ready to add fish to your diet? Consider adding it to your diet in pill form, or even prepare some fish dishes.

Head to your local grocery or drug store and pick up fish oil supplements derived from real fish. Supplements should contain both DHA and EPA as opposed to pesticides, PCBs, or traces of mercury. Be sure the amount of fish oil per capsule is less than three grams.

To get your fill by adding more fish to your diet, choose cold water fish dishes. Explore salt-water fish and wild-caught fish. Some popular and tasty types of cold-water fish include:

  • Smelt
  • Shad

Be sure to talk to your medical care providers to learn about safe additions to your diet. Certain groups of people, such as pregnant women, should limit their consumption of certain types of fish. Specifically, pregnant women should avoid consuming swordfish, king mackerel, and tilefish, while limiting their consumption of albacore tuna to no more than eight ounces per month.

If you have joint pain that will not subside with natural remedies or over-the-counter medications, it may be a sign of a more serious condition. Visit the orthopaedic specialists at UPMC online or call 1-877-471-0935 to schedule an appointment.

Cod Liver Oil Or Fish Oil

Fish oil for arthritis: Benefits and use

Fish oil is different from cod liver oil.

Cod liver oil contains oil from pressed cod livers only. It contains higher quantities of vitamins A and D than fish oil. The body needs these vitamins, but they can be harmful if people consume them in large quantities.

People who take fish oil or cod liver oil for arthritis will need to consume large amounts in order to obtain the benefits.

For this reason, fish oil is a more healthful source of omega-3s than cod liver oil, as people can consume large quantities without taking in too much vitamin A and D.

Rather than taking fish oil supplements, a person may prefer to include plenty of fish in their diet.

Good sources of omega-3s include:

  • salmon
  • sardines
  • mackerel

According to the Arthritis Foundation, eating 36 ounces of a variety of fish above between two and four times a week helps reduce inflammation and protect the heart.

When buying fish, consider the following points:

  • Is the fish likely to contain a high level of mercury? Check here.
  • Is it from a sustainable source? Check here.

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May Improve Bone Health

During old age, bones can begin to lose their essential minerals, making them more likely to break. This can lead to conditions like osteoporosis and osteoarthritis.

Calcium and vitamin D are very important for bone health, but some studies suggest that omega-3 fatty acids can also be beneficial.

People with higher omega-3 intakes and blood levels may have better bone mineral density (

Higher omega-3 intake is associated with higher bone density, which could help prevent bone disease. However, its unclear whether fish oil supplements are beneficial.

Combination Of Fish Oil With Other Nutrients Or Medication

The combination of fish oil and curcumin did not result in additional OA pain relief and seemed to dampen the reduction of OA pain and burden observed with fish oil alone. Combining fish oil with curcumin for additional benefits is a very new approach clinical trials are limited, with inconsistent results , and effects on OA pain relief have not yet been tested. In migraine patients, fish oil and curcumin were found to have synergistic effects on reduction of inflammatory markers and migraine attack frequency . However, in people at high risk of developing type 2 diabetes, the combination did not result in any complementary effects on glycaemic control and blood lipids , and in our study we did not find any synergistic effects on cardiometabolic risk factors and cerebrovascular function . Further studies are warranted to understand the interaction between fish oil and curcumin in humans and to ascertain whether there is a specific dose combination for fish oil and curcumin for synergistic effects and whether it is beneficial only in specific population groups .

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What Are Omega 3s

Omega 3s are one of several poly-unsaturated fatty acids that have physiologic roles in the body. Omega 3 and Omega 6 are essential PUFAs that are required for numerous functions in mammals, but they must be consumed through the diet. Omega 7 and 9 PUFAs can be formed endogenously. The distinction of 3, 6, 7, and 9 are based on the location of the final double bond in the chemical structure.

Omega 3s include EPA , DHA , and Alpha Lipoic Acid . Omega 6 PUFAs include linoleic acid and arachidonic acid this is the same AA that we are familiar with in the mechanism of action of NSAIDs .

Metabolism of AA leads to the production of inflammatory eicosanoids , including prostaglandin E2 . The metabolism of Omega 3 produces different forms of PGs and LTs that are less inflammatory .

Thus, increasing the amount of Omega 3s in the body leads to the replacement of AA in the cell membrane and decreased the production of inflammatory mediators. .

What Types Of Arthritis Benefit From Omega

Nutrition Advice : What Vitamins Help Arthritis?

Omega-3 fats have not been studied in all forms of arthritis. Current research suggests omega-3 fats are helpful for people with inflammatory arthritis, such as rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis. There is also some evidence that fish oils may help control symptoms of osteoarthritis and lupus .

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Best Fish For Arthritis

Adding more marine life to your meals could help calm inflammation.

Arthritis is for the most part a disease of inflammation. When your joints swell, turn red and feel warm to the touch, what youre witnessing and feeling are inflammatory processes in motion.

One way to calm inflammation is with medicine your doctor prescribes. Another way is to add a few keyanti-inflammatory foods to your diet. Among the most potent edible inflammation fighters are essential fatty acids called omega-3s particularly the kinds of fatty acids found in fish.

Omega-3s and Inflammation

Eicosapentaenoic acid and docosahexaenoic acid are called marine fatty acids because they come from fish. What makes these omega-3 sources worthwhile menu additions for people with arthritis is their ability to inhibit inflammation. Omega-3s interfere with immune cells called leukocytes and enzymes known as cytokines, which are both key players in the bodys inflammatory response.

The marine omega-3 fatty acids nip inflammation in the bud before it ignites. They really help to tamp down inflammation in the body on a cellular level, says Kim Larson, a Seattle-based nutritionist and Academy of Nutrition and Dietetics Spokesperson.

Research finds that people who regularly eat fish high in omega-3s are less likely to develop rheumatoid arthritis . And in those who already have the disease, marine omega-3s may help reduce joint swelling and pain.

Which Fish Are Best?


Farm-Raised or Wild-Caught?


About Upmc Orthopaedic Care

As a national leader in advanced orthopaedic care, UPMC treats a full range of musculoskeletal disorders, from the acute and chronic to the common and complex. Whether you have bone, muscle, or joint pain, we provide access to UPMCs vast network of support services for both surgical and nonsurgical treatments and a full continuum of care. As leaders in research and clinical trials with cutting-edge tools and techniques, UPMC Presbyterian Shadyside appears on U.S. News & World Reports rankings of the top hospitals in the country for orthopaedics.


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Range Of Therapeutic Applications Of Fish Oil

As discussed under clinical evidence for the anti-inflammatory effects of fish oil , fish oil has been found to have therapeutic effects in several inflammatory diseases. Fish oil has been studied most intensively in RA, where there is level 1 evidence for symptomatic improvement . There is level 2 evidence for a strong preventive effect against relapse in Crohn’s disease and against progression of renal failure in immunoglobulin A nephropathy . Some types of psoriasis have been shown to improve with oral fish oil given in anti-inflammatory doses . Fish oil improves control in systemic lupus erythematosus . In addition to this catalogue of disorders, which share an autoimmune-based inflammation in their pathogenesis, there is strong evidence for cardiovascular benefit with fish oil.

Does Fish Oil Help Your Joints

Fish oil for arthritis: Benefits and use

Living withjoint pain can make everyday activities difficult. Over-the-counter medications can help ease some ofthe discomfort associated with joint pain, but there is a natural alternativeworth trying.

Fish oil supplements are a popular alternative for those looking to relieve joint pain. It is made up of omega-3 fatty acids which contain anti-inflammatory properties. These fatty acids play a role in providing pain relief to many of your bodys joints.

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Dietary Sources Of N3 And N6 Polyunsaturated Fatty Acids

In seeking to alter the balance of n3 and n6 PUFAs in the tissues with therapeutic intent, it is necessary to understand which foods are rich in these fatty acids. This allows n3-rich items to be selected and n6-rich items to be avoided. In addition to fish oils, n3 PUFAs are found in the flesh of all marine fish, including crustaceans and shellfish. In fish and fish oils, n3 PUFAs are present as long chain PUFAs PUFAs. In certain vegetable oils, notably flaxseed, perilla and, to a lesser extent, canola oil, n3 PUFAs are present as the C18 PUFA -linolenic acid . In sunflower, cottonseed, safflower and soy oils, and the spreads manufactured from them, the main fatty acid is the n6 C18 PUFA linoleic acid . Olive oil and canola oil are rich sources of oleic acid , which is a monounsaturated fatty acid containing a single double bond in the n9 position. Oleic acid can be endogenously synthesized by humans, and so it is not an essential fatty acid .

Table 1 Dietary sources of fatty acids

Study Procedures And Outcome Measures

A detailed description of the study procedures has been published . Briefly, participants attended the research facility a total of four times , having refrained from medication, food and beverages other than water for 2h before the visit. During the first visit, anthropometric measures were taken, and participants were screened for suspected dementia . Then, participants were seated down for 10min before measurement of arterial compliance . Arterial pulse waveform analysis was used to assess the artery elasticity index of the small arteries, an indicator for endothelial dysfunction. Three consecutive measurements were taken and averaged for analysis. During the second visit, a venous blood sample was collected by a commercial pathology centre after an overnight fast to measure the inflammatory biomarker high-sensitivity CRP. Then, participants were asked to complete questionnaires regarding their chronic pain and OA burden, in addition to their general well-being. All assessments were repeated in the same order at the end of the 16-week trial.

Chronic pain measures

Well-being questionnaires

The participants perception of physical and mental well-being during the last 4weeks before their scheduled visit was assessed with the 36-Item Short Form Survey , which includes nine subscales . Each subscale has a maximum score of 100, indicating no disability, and the overall perception of quality of life was calculated by taking an average of all subscale scores.

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How To Take Bottled Fish Oil

Cleland et. al in their paper: Fish oil: what the prescriber needs to know highlight some important points about fish oil, how to take it, possible side effects and benefits. Here is their recommendation on taking bottled fish oil.

Fish oil has an unpleasant taste and odour which can be masked with flavoring.

An interesting way to take fish oil is to take it with juice. Pour 30-50 ml of fruit juice or a juice of your choice in two shot glasses.

Add a layer of fish oil to one glass.

Consume the fish oil and juice combination avoiding any contact with lips and thereafter have the juice from the other glass to remove any fish oil from lips.

It is advisable to take fish oil before solid meals without any fluids. Excess fluid causes the oil to float in stomach which gives the repeating taste.

If reflux is a problem then avoid taking any fluids or aerated drinks with fish oil and consume it prior to meals.

This ensures that it mixes with food and exits into the intestine.

If the problem still persists, you can lie down in the left lateral position which will ensure that the oil floats into the intestine.

Fish oil supplements can reduce the problem to a certain extent but since the oil from the capsules is released in the stomach these problems can occur.

Fact : Consuming One To Three Grams Of Fish Oil Per Day Can Decrease Joint Pain

Does Krill Oil Help Arthritis?

One-to-three grams of fish oil each day can help reduce the intensity of joint symptoms like morning stiffness, tenderness, swelling, and discomfort. The omega-3 fatty acids present in this amount can also increase blood flow throughout the body during exercise, which can help reduce joint pain and swelling.

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Does Fish Oil Help To Relieve Arthritis

Arthritis a disease where the joints of our bones swell and they become too painful to touch. For relief your doctor will prescribe you various medicines and some more to fight the side effects of the medicines. An easier way would be to include an anti inflammatory diet in your food. Some reasons why you can depend on fish oil for treating your arthritis is given below.

  • Fish oil contains two types of omega-3 fatty acids they are DHA and EPA . EPA and DHA can reduce inflammation, which is the basic cause of swelling and pain in patients.
  • Fish oil is used for treating rheumatoid arthritis.
  • When you consume fish oil regularly you are less likely to develop arthritis.

Fish Oil With Herbal Flavors For Arthritis:

This tends to improve the taste of the fish oil.

  • Take three to four tablespoon of fish oil and mix it with any herb as per your preference.
  • You could also add ginger juice.
  • Consume one spoonful of this mixture.

Tips And Precautions:

  • Most people can take fish oil even inlarge doses without trouble. But some have mild side effects. One needs to be careful while consuming fish oil. If you have any troubles then consult the doctor at once.
  • It causes belching and leaves a bad taste in the mouth
  • It can also result in heartburn, nausea, and diarrhea in some cases.

Due to high levels of mercury content, fishes like shark, swordfish, king mackarel, etc., should be avoided by pregnant women even though they are a good source of fish oil.

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Fish Oil Can Attenuate Pain

Tokuyama et. al have documented the role of unsaturated fatty acids in pain management.

Omega 3 fatty acids and their metabolites help in attenuating pain by other mechanisms other than reduction inflammation they also benefit in neuropathic pain.

Torres-Guzman et. al conducted an animal study where they demonstrated that oral supplementation or injections in the joints of omega 3 fatty acids reduced pain and swelling.

Supplementation with fish oil increases the level of essential fatty acids in the blood as well as synovial fluid and this associated with a decrease in pain.

An animal study reports that omega 3 fatty acid supplementation can serve as an adjunct to opiod therapy for managing pain and can attenuate side effects of morphine.

A study investigating the effect of fish oil supplementation in discogenic pain reported that fish oil can serve as an alternative to painkillers.

Individuals took 1200-2400mg essential fatty acids.

60% of the participants reported that their overall pain improved while 59% stopped taking prescribed NSAIDs. 80% were satisfied with their improvement.

Goldberg et. al reviewed the efficacy of omega 3 fatty acids in relieving inflammatory joint pain. 3-4 months supplementation with omega 3 fatty acids was associated with a reduction in pain intensity, duration of morning stiffness and number of tender joints.

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